A/HRC/33/31 governance reporting commensurate with the level of risk posed by their activities. This will help to identify, prevent and mitigate any risk of adverse human rights impacts. To guarantee all persons enjoy the rights to food and health as well as the benefits of science and its applications 11. States must take steps to ensure that global intellectual property regimes do not obstruct the realization of the right to food, hinder access to medicines, or impede the benefits of development from reaching the poor and marginalized, including through application of the trade-related aspects of intellectual property rights flexibilities, while at the same time ensuring that intellectual property regimes create appropriate incentives to help meet sustainable development objectives. Environmentally clean and sound technologies should be accessibly priced and broadly disseminated. The cost of their development should be equitably shared, and their benefits should be equitably distributed between and within countries. To ensure sovereign debt arrangements do not undercut the realization of human rights 12. States have committed to cooperate to mobilize maximum available resources for the progressive realization of human rights. Unsustainable debt burdens should not be permitted to threaten State efforts to fulfil their human rights obligations. All States would benefit from a permanent, fair and effective sovereign debt workout mechanism. All States, international financial institutions, relevant United Nations agencies, funds and programmes and the private sector, should cooperate to avoid sovereign debt crises by agreeing to guidelines that ensure sustainable, transparent lending and borrowing that benefits and is accountable to people, taking into consideration the guiding principles on foreign debt and human rights endorsed by the Human Rights Council. To address climate harms to human rights 13. Climate change affects people everywhere. Yet, the poorest and most marginalized individuals, communities and countries that have contributed the least to greenhouse emissions often bear the greatest burden. Efforts to mitigate and adapt to the impacts of climate change should therefore meet the special needs and circumstances of developing countries and of vulnerable and marginalized persons everywhere. For example, harmful fossil fuel and agricultural subsidies, both direct and indirect, should be phased out with safeguards that minimize the impact on the poorest and most vulnerable. Conversely, carbon taxes, with appropriate safeguards to minimize impacts on the poorest and most vulnerable, could be designed to internalize environmental externalities and finance sustainable development efforts. To align economic policies and institutions with human rights standards 14. A road map should be put in place for economic governance reforms that ensure fair representation of emerging and developing countries in international financial and economic decision making, prevent future economic crises and promote sustainable, inclusive economic progress. Policy coherence, particularly human rights policy coherence, will be critical for the successful implementation of the 2030 Agenda. This will entail taking measures to ensure coherence between current international legal regimes for trade, finance, and investment on the one hand and norms and standards for labour, the environment, human rights, equality and sustainability on the other hand. 14