A/HRC/45/39 human rights risks and State investor contract negotiations: guidance for negotiations” (A/HRC/17/31/Add.3); (p) Make all efforts to develop international cooperation, as an additional mechanism in the efforts for sustainable development, particularly in developing countries, for promoting the international exchange of experiences and assistance, taking into account the needs and the economic plans of the recipient countries and fully respecting human rights; (q) Promote the development of international trade as a means of favouring development in all countries, while taking into account in particular the interests of developing countries, and ensure that trade exchanges contribute to the realization of the Sustainable Development Goals and targets; (r) Increase efforts to ensure the protection of the environment, to reduce the degradation and pollution of oceans and seas, to restore ecosystems, to promote the sustainable management of forests and mangroves, to reduce and stop desertification and to end the degradation of soil and the loss of biodiversity; (s) Integrate climate action measures into national policies and plans and intensify, in accordance with their responsibilities, efforts to stop and reverse climate change by reducing and eliminating carbon emissions into the atmosphere, attenuate and mitigate the adverse effects already produced by climate change and assist developing countries, in particular the least developed countries, in the planning and management of responses to climate change events, including by focusing on women, young people and local and marginalized communities. United Nations agencies, regional economic commissions, human rights treaty bodies and special procedure mandate holders 86. International organizations, regional economic commissions, human rights treaty bodies and special procedure mandate holders should promote the development of a multilateral approach in the consideration of all questions of global interest, in order to be able to elaborate and adopt global solutions, taking into account the interests of all States and of the international community as a whole. 87. United Nations entities and specialized agencies and other international organizations should include on their agenda and consider items related to the Sustainable Development Goals and targets, remain in permanent contact with their member States, organize consultations and meetings, assist them and promote programmes and activities that contribute to the realization of the Goals and targets. 88. The relevant international organizations should analyse the impact of the recent infectious diseases that have affected the world, consider and recommend measures to be taken in order to better prepare States and communities to respond to such diseases, reduce human suffering, continue sustainable development and strengthen respect for human rights. 89. The regional commissions should continue to periodically examine the status of implementation by States of the Sustainable Development Goals and targets and assist States to review their implementation, adopt new plans and programmes and apply adequate measures to implement them, bearing in mind the principle of leaving no one behind. 90. The human rights treaty bodies, in the examination of periodic reports submitted by States parties to the human rights treaties and of individual communications, should give due attention to the application of the treaty obligations related to the realization of the Sustainable Development Goals and targets, in particular the obligation to eliminate discrimination against all, including members of vulnerable groups. 19